부산대학교 약학대학 [2008, 학사]
부산대학교 약학대학 [2012, 박사]

한국과학기술원 Post-Doc Fellow [2012-2017, 전상용 교수 연구실]
University of Michigan, Ann Arbor, Research Scientist [2017-2020, James Moon 교수 연구실]
이화여자대학교 약학대학 조교수 [2020-2023]
이화여자대학교 약학대학 부교수 [2023-현재]

세포사멸조절용 나노/바이오메디슨 개발 및 평가
면역계 조절용 나노/바이오메디슨 개발 및 평가
마이크로바이옴 조절용 나노/바이오 메디슨 개발 및 평가

"Hyaluronic acid-bilirubin Nanomedicine as a Tumor Microenvironment-responsive Nanomedicine for Targeted Cancer Therapy" International Journal of Nanomedicine, 2024 May 27 (IF 8.0., JCR top 5%)
"Anti-oxidative Hyaluronic acid-bilirubin Nanomedicine targeting Activated Hepatic Stellate Cells for Anti-hepatic Fibrosis Therapy" ACS Nano, 2024 Feb 01 (IF 17.1)
“Hyaluronic acid-bilirubin nanomedicine-based combination chemoimmunotherapy” Nature Communication, 2023 Aug 08, 14:4771 (IF 16.6) *Co-corresponding authors
“Oral Nanomedicine for modulating immunity, intestinal barrier functions, and gut microbiome” Advanced Drug Delivery Review, 2021 Dec, 179, 114021 (IF 17.873) *Co-corresponding authors
“Hyaluronic acid-bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome, and immune responses in colitis.” Nature Materials. 2020 Jan 1: 19 (1): 118-126. (IF 43.841)
“Biotinylated bilirubin nanoparticles as a tumor microenvironment-responsive drug delivery system for targeted cancer therapy” Advanced Science. 2018 Apr 24; 5(6):1800017. (IF 15.840).
“Bilirubin nanoparticles ameliorate allergic lung inflammation in a mouse model of asthma” Biomaterials. 2017 Sep;140:37-44. (IF 12.479). *These authors contributed equally to this work.
“Multi-stimuli-responsive bilirubin nanoparticles for anticancer therapy.” Angewandte chemie. 2016 Aug 26;55(36):10676-10680. (IF 15.336). Selected by the editors of Angewandte Chemie as a “Hot paper” (top 10% of all Angewandte publications).
“Bilirubin nanoparticles as a nanomedicine for anti-inflammation therapy.” Angewantde chemie. 2016 Jun 20;55(26):7460-7463. (IF 15.336)

빌리루빈기반 나노메디슨 임상 1상.
기술 이전 10억 이상 3건.

● FACS

● HPLC

● RT-PCR

● 동결건조기

항암제, 약물전달, 나노메디슨, 마이크로바이옴, 면역계